Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry
نویسندگان
چکیده
منابع مشابه
Direct measurement of protein binding energetics by isothermal titration calorimetry.
Of all the techniques that are currently available to measure binding, isothermal titration calorimetry is the only one capable of measuring not only the magnitude of the binding affinity but also the magnitude of the two thermodynamic terms that define the binding affinity: the enthalpy (AH) and entropy (AS) changes. Recent advances in instrumentation have facilitated the development of experi...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2018
ISSN: 2041-1723
DOI: 10.1038/s41467-018-03263-3